MaClean N, Turner S
J Embryol Exp Morphol. 1976 Apr;35(2):261-6.
Tadpoles of Xenopus laevis reared in water containing 0-01% propylthiouracil continue to grow but fail to develop or metamorphose. The haemoglobin of such tadpoles has been extracted in buffer, converted to a cyanmet form, and run on polyacrylamide gels. The developmentally retarded tadpoles are found to possess adult-type haemoglobin rather than the tadpole type which normally characterizes their developmental stage.
在含有0.01%丙硫氧嘧啶的水中饲养的非洲爪蟾蝌蚪能够继续生长，但无法发育或变态。已在缓冲液中提取了此类蝌蚪的血红蛋白，将其转化为氰化高铁血红蛋白形式，并在聚丙烯酰胺凝胶上进行电泳。结果发现，发育迟缓的蝌蚪拥有成年型血红蛋白，而非正常情况下与其发育阶段特征相符的蝌蚪型血红蛋白。
