Devriès J
J Embryol Exp Morphol. 1976 Apr;35(2):403-24.
Embryos of Eisenia foetida (Spiralia) have been cultivated with [3H]uracil precursor of RNA at different stages of development from egg to gastrula. The results show that ribonucleic acid synthesis detected by autoradiography begins precociously. During segmentation messenger RNAs are produced by interphase nuclei and liberated in cytoplasm cyclically at mitosis. After the blastula stage rRNAs (nucleoli), which can migrate through the nuclear membranes, predominate. The blastomeres, which contain polar plasm and also mesoderm, already known for its controlling part in embryogenesis after gastrulation, are the seats of the increasingly important ribonucleic acid synthesis. These genetic transcriptions, which are inhibited by actinomycin D, are implicated in the determination of the blastomers and postblastular differentiation. Only the messages required for the segmentation divisions pre-exist in the undivided egg.
在从卵到原肠胚的不同发育阶段，用RNA的[3H]尿嘧啶前体培养了赤子爱胜蚓（螺旋虫纲）的胚胎。结果表明，通过放射自显影检测到的核糖核酸合成早熟开始。在卵裂期间，信使核糖核酸由间期核产生，并在有丝分裂时周期性地释放到细胞质中。囊胚期后，能够穿过核膜的核糖体核糖核酸（核仁）占主导地位。含有极质以及中胚层的卵裂球是核糖核酸合成日益重要的场所，中胚层在原肠胚形成后的胚胎发育中起控制作用，这一点已为人所知。这些受放线菌素D抑制的基因转录与卵裂球的决定和囊胚后期分化有关。只有卵裂所需的信息预先存在于未分裂的卵中。
