吲哚金黄杆菌和脑膜炎败血金黄杆菌对头孢吡肟和头孢匹罗的敏感性。
Susceptibilities of Chryseobacterium indologenes and Chryseobacterium meningosepticum to cefepime and cefpirome.
作者信息
Hsueh P R, Teng L J, Yang P C, Ho S W, Luh K T
机构信息
Department of Laboratory Medicine, National Taiwan University Hospital, Taipei.
出版信息
J Clin Microbiol. 1997 Dec;35(12):3323-4. doi: 10.1128/jcm.35.12.3323-3324.1997.
Abstract
In vitro activities of cefepime and cefpirome against 96 isolates of Chryseobacterium indologenes and 21 of C. meningosepticum were determined by the agar dilution method. Overall, cefepime was more active than cefpirome against C. indologenes (MIC at which 50% of the isolates were inhibited [MIC50] and MIC90, 4 and 16 microg/ml, respectively, for cefepime and 8 and 128 microg/ml, respectively, for cefpirome). Both agents had poor potency against C. meningosepticum (MIC50 and MIC90, 64 and >256 microg/ml, respectively, for cefepime and 128 and >256 microg/ml, respectively, for cefpirome).
摘要
采用琼脂稀释法测定了头孢吡肟和头孢匹罗对96株产吲哚金黄杆菌及21株脑膜炎败血金黄杆菌的体外抗菌活性。总体而言，头孢吡肟对产吲哚金黄杆菌的活性强于头孢匹罗（头孢吡肟的50%抑菌浓度[MIC50]和90%抑菌浓度[MIC90]分别为4和16μg/ml，头孢匹罗的MIC50和MIC90分别为8和128μg/ml）。两种药物对脑膜炎败血金黄杆菌的活性均较差（头孢吡肟的MIC50和MIC90分别为64和>256μg/ml，头孢匹罗的MIC50和MIC90分别为128和>256μg/ml）。
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