Celis H, De Cort P, Fagard R, Thijs L, Staessen J A
Department of Molecular and Cardiovascular Research, Faculty of Medicine, University of Leuven, Belgium.
J Hum Hypertens. 1997 Oct;11(10):673-7. doi: 10.1038/sj.jhh.1000517.
This study investigated the period of time that blood pressure (BP) should be measured at home in older patients in order to obtain steady BP values. Thirty-six men and 38 women (> or =60 years) were recruited at one family practice. At one office visit the family physician measured supine, sitting and standing BPs three times consecutively in each position. During 10 consecutive days, BP was measured at home five times daily. The supine and standing BPs were measured once in the morning and in the evening and the sitting BP once at noon. These home BP values were averaged over the first day (1-day), over the first 3 days (3-day) and all 10 days (10-day) of measurements. In both the supine (-5.1 mm Hg) and sitting (-3.8 mm Hg) positions the 10-day average systolic home BP was significantly lower than the corresponding office BP. The opposite was observed for the 10-day average standing home BP values (+7.3/+3.4 mm Hg). Comparison of the 3-day and 10-day average home BP values showed only a significantly lower 10-day than 3-day systolic BP level in the supine position (-1.1 mm Hg, 95% CI -1.9 to -0.2 mm Hg). Repeated measures ANOVA, showed a small but significant decrease over time only for the supine systolic home BP (-0.29 mm Hg per day, 95% CI -0.49 to -0.08 mm Hg per day). We conclude that in older subjects, 3 days of home measurements may suffice to obtain steady values for the sitting and standing BPs. A longer interval might be required for the supine BP.
本研究调查了老年患者在家中测量血压以获取稳定血压值所需的时间。在一家家庭诊所招募了36名男性和38名女性(年龄≥60岁)。在一次门诊就诊时,家庭医生在每个体位连续测量仰卧位、坐位和站立位血压3次。在连续10天内,每天在家中测量血压5次。仰卧位和站立位血压在早上和晚上各测量一次,坐位血压在中午测量一次。这些家庭血压值在测量的第一天(1天)、前3天(3天)和全部10天(10天)进行平均。在仰卧位(-5.1 mmHg)和坐位(-3.8 mmHg),10天的家庭收缩压平均值均显著低于相应的诊室血压。而10天的家庭站立位血压平均值则相反(+7.3/+3.4 mmHg)。比较3天和10天的家庭血压平均值发现,仅仰卧位10天的收缩压水平显著低于3天(-1.1 mmHg,95%CI -1.9至-0.2 mmHg)。重复测量方差分析显示,仅仰卧位家庭收缩压随时间有小幅但显著的下降(每天-0.29 mmHg,95%CI -0.49至-0.08 mmHg/天)。我们得出结论,在老年受试者中,3天的家庭测量可能足以获得坐位和站立位血压的稳定值。仰卧位血压可能需要更长的测量间隔。