Bardhan P K
Clinical Sciences Division, International Centre for Diarrhoeal Diseases Research, Bangladesh, Dhaka.
Clin Infect Dis. 1997 Nov;25(5):973-8. doi: 10.1086/516067.
Helicobacter pylori infection has a worldwide distribution, and it has distinct epidemiological features in developing countries. In contrast to that in developed countries, H. pylori infection in developing countries seems to be nearly universal, beginning in early childhood. Children become infected in the first few months of life; in some communities as many as 50% of the children are infected by the age of 5 years, and up to 90% are infected by the time they reach adulthood. In some developing countries with improvements in industrialization, socioeconomic conditions, and hygiene, infection rates are lower. The incidence of H. pylori infection, determined indirectly, also suggests a rate several times higher than that in developed countries. Marked differences in H. pylori seroprevalence have been observed between various ethnic and racial groups. Although the mode of transmission of H. pylori remains uncertain, evidence suggests person-to-person transmission occurs.
幽门螺杆菌感染在全球范围内均有分布，且在发展中国家具有独特的流行病学特征。与发达国家不同，发展中国家的幽门螺杆菌感染似乎几乎是普遍现象，始于儿童早期。儿童在出生后的头几个月就会被感染；在一些社区，多达50%的儿童在5岁时被感染，到成年时感染率高达90%。在一些工业化、社会经济状况和卫生条件有所改善的发展中国家，感染率较低。通过间接测定得出的幽门螺杆菌感染发病率也表明，该发病率比发达国家高出数倍。在不同的民族和种族群体之间，已观察到幽门螺杆菌血清阳性率存在显著差异。尽管幽门螺杆菌的传播方式仍不确定，但有证据表明其通过人传人发生传播。
