Kron S J
Center for Molecular Oncology, University of Chicago, Chicago, IL 60637, USA.
Trends Microbiol. 1997 Nov;5(11):450-4. doi: 10.1016/S0966-842X(97)01131-1.
The recent discovery that some laboratory strains of Saccharomyces cerevisiae are capable of limited filamentous growth has stimulated genetic analysis of dimorphism in this microorganism. The puzzle of why most strains are nonfilamentous is now resolved. Remarkably, a single point mutation with broad consequences separates these domesticated yeast from their wild ancestors.
最近发现一些酿酒酵母实验室菌株能够进行有限的丝状生长,这激发了对这种微生物中双态性的遗传分析。为什么大多数菌株不形成丝状的谜题现在已经解开。值得注意的是,一个具有广泛影响的单点突变将这些驯化酵母与其野生祖先区分开来。