Nakashima T, Nishimura Y, Sakai N, Yamada H, Hara A
Department of Neurosurgery, Gifu University School of Medicine, Japan.
Childs Nerv Syst. 1997 Oct;13(10):563-6. doi: 10.1007/s003810050139.
A Down syndrome patient with germinoma developing in the cerebral hemisphere is reported. A review of the literature yielded only 14 cases of Down syndrome with brain tumors, including our case. This finding of brain tumors in patients with Down syndrome may reflect chance occurrence. However, it is of interest in this regard that in 6 of the 14 (43%) reported cases the lesions were intracranial germ cell tumors.