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亲本拮抗、亲缘关系不对称与基因组印记

Parental antagonism, relatedness asymmetries, and genomic imprinting.

作者信息

Haig D

机构信息

Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA 02138, USA.

出版信息

Proc Biol Sci. 1997 Nov 22;264(1388):1657-62. doi: 10.1098/rspb.1997.0230.

Abstract

The theory of inclusive fitness can be modified to consider separate coefficients of relatedness for an individual's maternal and paternal alleles. A gene is said to have parentally antagonistic effects if it has an inclusive fitness benefit when maternally derived, but an inclusive fitness cost when paternally derived (or vice versa). Parental antagonism favours the evolution of alleles that are expressed only when maternally derived or only when paternally derived (genomic imprinting).

摘要

广义适合度理论可以进行修正,以考虑个体母系和父系等位基因的不同亲缘系数。如果一个基因在母系遗传时具有广义适合度益处,但在父系遗传时具有广义适合度代价(反之亦然),那么就称该基因具有亲代拮抗效应。亲代拮抗有利于仅在母系遗传时或仅在父系遗传时表达的等位基因的进化(基因组印记)。

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