Canady R A, Hanley J E, Susten A S
Agency for Toxic Substances and Disease Registry, Public Health Service, U.S. Department of Health and Human Services, Atlanta, Georgia, USA.
Risk Anal. 1997 Oct;17(5):527-32. doi: 10.1111/j.1539-6924.1997.tb00894.x.
On the basis of discussion and analysis during and following an ATSDR science panel on the bioavailability of mercury in soils, it is apparent that the default assumption of 100% relative bioavailability for mercury-contaminated soils is excessively conservative. However, current knowledge does not allow the development of default assumptions or guidelines for determining relative bioavailability of mercury in soils. Until such default assumptions or guidelines can be developed, site-specific assays of bioavailability, preferably using either animal bioassays or validated in vitro techniques, may provide the best approach for estimating soil-mercury bioavailability.
在有毒物质和疾病登记处（ATSDR）关于土壤中汞生物有效性的科学小组会议期间及之后进行的讨论和分析的基础上，很明显，对于汞污染土壤，默认假设其相对生物有效性为100%过于保守。然而，目前的知识水平尚无法制定出用于确定土壤中汞相对生物有效性的默认假设或指导方针。在能够制定出此类默认假设或指导方针之前，针对特定场地的生物有效性测定（最好使用动物生物测定法或经过验证的体外技术）可能是估算土壤汞生物有效性的最佳方法。
