Arricau N, Hermant D, Waxin H, Popoff M Y
Unité de Génétique des Bactéries intracellulaires, Unité INSERM 389, Institut Pasteur, Paris, France.
Res Microbiol. 1997 Jan;148(1):21-6. doi: 10.1016/S0923-2508(97)81896-7.
Analysis of the nucleotide sequence of a 4-kb DNA fragment located between the sip and iag loci on Salmonella typhi chromosome revealed three open reading frames, termed sipF, ctpA and stpA. The 82-amino-acid (aa) sipF product showed extensive similarity to the lacP protein from S. typhimurium. The StpA protein (535 aa) exhibited significant similarity to both Yersinia enterocolitica YopE cytotoxin and YopH tyrosine phosphatase. The CtpA polypeptide (130 aa) might be the molecular chaperone of the StpA protein.
对伤寒沙门氏菌染色体上位于sip和iag基因座之间的一个4 kb DNA片段的核苷酸序列分析，揭示了三个开放阅读框，分别称为sipF、ctpA和stpA。82个氨基酸（aa）的sipF产物与鼠伤寒沙门氏菌的lacP蛋白有广泛的相似性。StpA蛋白（535个氨基酸）与小肠结肠炎耶尔森氏菌YopE细胞毒素和YopH酪氨酸磷酸酶都有显著的相似性。CtpA多肽（130个氨基酸）可能是StpA蛋白的分子伴侣。
