Campanile T M, St Clair D A, Benaim M
Emergency Department, 96th Medical Group, Eglin Air Force Base, Florida, USA.
J Emerg Med. 1997 Nov-Dec;15(6):769-74. doi: 10.1016/s0736-4679(97)00182-0.
The objective of this study was to compare the rates of healing for patched and non-patched traumatic corneal epithelial defects (CEDs) after 1 day of treatment. To achieve this we initiated a randomized, controlled, prospective, clinical investigation comparing patching vs. non-patching of CEDs. Patients were evaluated initially and at 24 h using slit lamp biomicroscopy, and each corneal epithelial defect was documented on standardized initial and follow-up grid sheets. Percentage of healing and healing rates were determined by comparing the grid sheets. Our results found no significant difference in abrasion size between the two groups, but there was found to be a significantly improved rate of healing at follow-up in non-patched patients. This study demonstrates a significant improvement in the healing rate of traumatic CEDs in the non-patched group as compared to the patched group; therefore, the use of eye patching is not mandatory for corneal epithelial healing to occur.
本研究的目的是比较治疗1天后 patched 和未patched 的外伤性角膜上皮缺损(CED)的愈合率。为实现这一目标,我们开展了一项随机、对照、前瞻性临床研究,比较 CED 的patched 与未patched 情况。最初以及在24小时时使用裂隙灯生物显微镜对患者进行评估,并在标准化的初始和随访网格纸上记录每个角膜上皮缺损情况。通过比较网格纸来确定愈合百分比和愈合率。我们的结果发现两组之间擦伤大小无显著差异,但发现未patched 患者在随访时愈合率显著提高。本研究表明,与patched 组相比,未patched 组外伤性 CED 的愈合率有显著提高;因此,角膜上皮愈合并不一定需要使用眼罩。