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骨髓移植后人类疱疹病毒6型脑炎:更昔洛韦治疗成功

Human herpes virus-6 encephalitis after bone marrow transplantation: successful treatment with ganciclovir.

作者信息

Mookerjee B P, Vogelsang G

机构信息

Division of Hematologic Malignancies, Johns Hopkins Oncology Center, Baltimore, MD 21287-8985, USA.

出版信息

Bone Marrow Transplant. 1997 Nov;20(10):905-6. doi: 10.1038/sj.bmt.1700988.

DOI:10.1038/sj.bmt.1700988
PMID:9404935
Abstract

Here we report a case that presented with sudden onset of neurological symptoms and was treated with ganciclovir. Polymerase chain reaction analysis for human herpes virus-6 (HHV-6) from his cerebrospinal fluid was later found to be positive. He subsequently recovered with minimal residual neurological symptoms. Encephalitis secondary to this virus may be more common than previously thought in patients undergoing bone marrow transplantation. This condition should be considered in the differential diagnosis of sudden onset neurological symptoms after bone marrow transplantation.

摘要

在此,我们报告一例突然出现神经症状并接受更昔洛韦治疗的病例。后来发现其脑脊液的人疱疹病毒6型(HHV - 6)聚合酶链反应分析呈阳性。他随后康复,仅遗留轻微的神经症状。在接受骨髓移植的患者中,这种病毒继发的脑炎可能比之前认为的更为常见。在骨髓移植后突然出现神经症状的鉴别诊断中应考虑这种情况。

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J Neurovirol. 2006 Aug;12(4):284-93. doi: 10.1080/13550280600880772.
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