未经治疗的慢性肾衰竭患者及血液透析患者的甲状旁腺激素血浆水平。

Parathyroid hormone plasma level in untreated chronic renal failure and in hemodialyzed patients.

作者信息

Fuss M, De Backer M, Brauman J, Nijs-Dewolf N, Manderlier T, Brauman H, Corvilain J

出版信息

Nephron. 1976;17(2):144-54. doi: 10.1159/000180720.

Abstract

In 42 untreated patients at various stages of chronic renal failure, plasma level of parathyroid hormone was directly proportional to the degree of renal failure and inversely proportional to the serum calcium level. Plasma parathyroid hormone levels were frequently elevated in 21 patients undergoing regular dialysis treatment, in spite of normal levels of serum total calcium and magnesium. Serum-ionized calcium levels measured in dialyzed patients were usually reduced and inversely correlated with the creatinine levels. Parathyroid hormone levels were correlated with the creatinine levels, but the inverse relationship with ionized calcium was not significant.

摘要

在42例处于慢性肾衰竭不同阶段的未治疗患者中，甲状旁腺激素的血浆水平与肾衰竭程度呈正比，与血清钙水平呈反比。21例接受常规透析治疗的患者，尽管血清总钙和镁水平正常，但甲状旁腺激素的血浆水平经常升高。透析患者测定的血清离子钙水平通常降低，且与肌酐水平呈负相关。甲状旁腺激素水平与肌酐水平相关，但与离子钙的负相关关系不显著。