Archer D F, Josimovich J B
Obstet Gynecol. 1976 Aug;48(2):155-7.
To determine if elevated serum prolactin hPRL inhibits ovarian steroidogenesis and contributes to the amenorrhea associated with galactorrhea syndromes, the following study was performed. Four women with amenorrhea, galactorrhea, and elevated serum hPRL levels were treated with menopausal gonadotropins (Pergonal) for the associated infertility. Urinary estrogen response was comparable to that in normal ovulatory women in each patient. Ovulation occurred in 3 of the 4 women with resultant conception and normal pregnancies. There was no evidence to support the contention that elevated hPRL interferes with ovarian function.
为了确定血清催乳素（hPRL）升高是否会抑制卵巢甾体激素生成并导致与溢乳综合征相关的闭经，进行了以下研究。对4名患有闭经、溢乳且血清hPRL水平升高的女性，使用绝经期促性腺激素（ Pergonal）治疗相关的不孕症。每位患者的尿雌激素反应与正常排卵女性相当。4名女性中有3名排卵，随后受孕并正常妊娠。没有证据支持hPRL升高会干扰卵巢功能这一观点。
