Bouzourene H, Genton C Y
Institut universitaire de Pathologie, Lausanne, Suisse.
Arch Anat Cytol Pathol. 1997;45(4):192-8.
In contrast with other malignant tumors, the prognosis of malignant ovarian mucinous tumors has not been improved. In fact, their are diagnosed late and their therapy is often inadequate. The absence of consensus concerning the histological criteria of borderline tumors and mucinous carcinomas has led to diverse classifications which are often not reproducible and are also responsible for heterogeneous results concerning patient survival. Unfortunately, none of the biochemical, molecular biology or cytometric markers which have been studied up until now can be used for differential diagnosis. Another particularity of mucinous tumors consists of their association with other ovarian tumors, mural nodules which are reactive or tumor proliferations and which might influence the prognosis of the mucinous tumor, when their are malignant, and peritoneal pseudomyxoma and appendicular mucocele which give rise to problems related to their relation.
与其他恶性肿瘤相比，恶性卵巢黏液性肿瘤的预后并未得到改善。事实上，它们往往诊断较晚，治疗也常常不充分。关于交界性肿瘤和黏液性癌的组织学标准缺乏共识，导致了多种分类，这些分类往往不可重复，也导致了关于患者生存的结果不一致。不幸的是，迄今为止所研究的生化、分子生物学或细胞计量学标志物均不能用于鉴别诊断。黏液性肿瘤的另一个特点是它们与其他卵巢肿瘤、反应性或肿瘤性增生的壁结节相关，当这些结节为恶性时，可能会影响黏液性肿瘤的预后，以及与腹膜假黏液瘤和阑尾黏液囊肿相关，它们会引发与两者关系相关的问题。
