Dargent D
Service de gynécologie-obstétrique, hôpital Edouard-Herriot, Lyon.
Rev Prat. 1997 Oct 1;47(15):1684-9.
Vulvar cancer develops onto vulvar dystrophies. Its development is linked with HPV infection in half of the cases. It can appear as a carcinoma in situ, a microinvasive carcinoma or a true invasive carcinoma. Prurit is the most common symptom. In situ carcinomas have to be treated by skinning vulvectomies. Radical vulvectomy was considered as mandatory for truly infiltrative cancers. One prefers today use the "wider local excision". However lymphadenectomy is still mandatory (less than 1 mm) in case of very limited dermal infiltration.
外阴癌由外阴营养不良发展而来。其发生在半数病例中与HPV感染有关。它可表现为原位癌、微浸润癌或真正的浸润癌。瘙痒是最常见的症状。原位癌必须通过外阴皮肤切除术治疗。对于真正浸润性癌症,根治性外阴切除术曾被认为是必要的。如今人们更倾向于采用“广泛局部切除术”。然而,在真皮浸润非常有限的情况下,淋巴结清扫术(浸润小于1毫米)仍然是必要的。