Vandersteen D P, Wiemerslage S J, Cohen M B
Department of Pathology, University of Iowa, Iowa City 52242-1009, USA.
Diagn Cytopathol. 1997 Dec;17(6):480-3. doi: 10.1002/(sici)1097-0339(199712)17:6<480::aid-dc20>3.0.co;2-h.
Prostatic duct adenocarcinoma is a rare tumor which typically involves the prostatic urethra as its primary site. Due to this unique location, prostatic duct adenocarcinoma may shed cells into urine specimens which may be detected by cytologic techniques. This report describes the cytologic and histologic features of a case of prostatic duct adenocarcinoma involving the prostatic urethra. Key features which differentiate this neoplasm from the more common transitional carcinomas and the potentially confounding prostatic acinar adenocarcinomas include epithelial clusters with prominent nuclear overlap and nuclear grooves. A comparison to the five previously reported cases is presented.
前列腺导管腺癌是一种罕见的肿瘤,其主要原发部位通常累及前列腺尿道。由于这一独特的位置,前列腺导管腺癌可能会将细胞脱落到尿液标本中,而这些细胞可通过细胞学技术检测到。本报告描述了一例累及前列腺尿道的前列腺导管腺癌的细胞学和组织学特征。将这种肿瘤与更常见的移行细胞癌以及可能造成混淆的前列腺腺泡腺癌区分开来的关键特征包括具有明显核重叠和核沟的上皮细胞簇。文中还与之前报道的5例病例进行了比较。