Martis G, Mikó I, Szendröi T, Kathy S, Kovács J, Hajdu Z
Department of General Surgery, Kenézy Teaching Hospital, Hungary.
Acta Chir Hung. 1997;36(1-4):221-2.
Diffuse bleeding from parenchymatous organs at conventional surgery is eliminated with the usual methods coagulation tamponade or styches. We performed experimental series at 9 dogs. After resection of spleen, liver, pancreas and kidney, the bleeding surface was covered by collagen fleece coated with fibrin glue (TachoComb). Postoperatively 7 days, 10 days, 14 days and 28 days we made a relaparotomy. Then the results were analyzed macroscopically and microscopically. In the abdominal cavity neither significant quantity of blood nor greater adhesions were detected. At all cases the fibrin glue was found on place were it was put before. Histologically a perfect wound healing experienced. The fibrin glue (TachoComb) using at diffuse parenchymatous organs' bleeding give a very good results when the wound area is at least 1 cm beyond the immediate wound margin and the fibrin glue is applied onto the wound and pressed on it for 4-5 minutes.
传统手术中实质器官的弥漫性出血通常采用凝血填塞或缝合等方法来消除。我们对9只狗进行了实验系列。切除脾脏、肝脏、胰腺和肾脏后，出血表面用涂有纤维蛋白胶（TachoComb）的胶原绒覆盖。术后7天、10天、14天和28天进行再次剖腹手术。然后对结果进行宏观和微观分析。在腹腔内未检测到大量血液或更多粘连。在所有病例中，纤维蛋白胶都在之前放置的位置被发现。组织学上伤口愈合良好。当伤口面积至少超出直接伤口边缘1厘米，且将纤维蛋白胶涂覆在伤口上并按压4 - 5分钟时，在弥漫性实质器官出血时使用纤维蛋白胶（TachoComb）可取得非常好的效果。
