[Animal experiment studies of hemostasis using the fibrinogen adhesive system on the liver and spleen in coagulation disorders].

Fresh resection areas after partial resection of liver and lien in rabbits were repaired and sealed by a fibrin film on conditions of hemorrhagic tendency and increased fibrinolysis. A strong damage in the wound area in the same way as in organic injury originates from these pathologic conditions. A premature demarcation of the external wound strata especially in raised fibrinolysis takes place by reason of the parenchymal necrosis though the fibrinogen is cross-linked to an intact film independent of the common circulation and clotting relations. An abundant wound revision is recommended before using the fibrin adhesive to prevent an after-bleeding.