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用于生物材料的新型钛合金:力学性能、腐蚀性能及细胞毒性研究

New titanium alloys for biomaterials: a study of mechanical and corrosion properties and cytotoxicity.

作者信息

Kim T I, Han J H, Lee I S, Lee K H, Shin M C, Choi B B

机构信息

Department of Prosthodontics, School of Dentistry, Kyung Hee University, Seoul, Korea.

出版信息

Biomed Mater Eng. 1997;7(4):253-63.

PMID:9408577
Abstract

Three new titanium alloys with Zr, Nb, Ta, Pd and In as alloying elements were developed and compared with currently used implant metals, namely, pure Ti and Ti-6Al-4V alloy, in terms of mechanical and corrosion properties, and cytotoxicity. New alloys showed comparable mechanical properties with that of the Ti-6Al-4V alloy, but increased corrosion potential, somewhat decreased breakdown potential and increased corrosion rate. There were no significant differences in cell growth on the surface of the various metal specimens, indicating that the cells cannot differentiate between the passivated surfaces of the various Ti metals.

摘要

研发了三种以锆、铌、钽、钯和铟作为合金元素的新型钛合金,并将其与目前使用的植入金属(即纯钛和Ti-6Al-4V合金)在机械性能、腐蚀性能和细胞毒性方面进行了比较。新型合金的机械性能与Ti-6Al-4V合金相当,但腐蚀电位增加,击穿电位略有降低,腐蚀速率增加。在各种金属试样表面上的细胞生长没有显著差异,这表明细胞无法区分各种钛金属的钝化表面。

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