Kume N, Suga K, Nishigauchi K, Shimizu K, Matsunaga N
Department of Radiology, Yamaguchi University School of Medicine, Japan.
Clin Nucl Med. 1997 Dec;22(12):825-31. doi: 10.1097/00003072-199712000-00004.
The appearance of hepatic adenomas on CT and MRI are highly variable because of their varied histopathology, and images of adenomas are at times indistinguishable from those of other hepatic tumors. The authors present two patients with hepatic adenomas with extremely atypical CT and MRI manifestations demonstrating a "nodule-in-nodule" appearance. Radionuclide imaging in both patients showed decreased Ga-67 uptake in the adenomas compared to normal liver, negative colloid (Tc-99m phytate) uptake in the adenomas, and early uptake and subsequent retention of Tc-99m PMT. This correctly characterized the unique histopathologic features of the resected tumors. Radionuclide imaging using a combination of radiotracers may play an important role in aiding the diagnosis of this rare benign tumor, despite variable CT and MRI appearances.
由于肝腺瘤的组织病理学各不相同，其在CT和MRI上的表现差异很大，腺瘤的影像有时与其他肝脏肿瘤难以区分。作者报告了两名患有肝腺瘤的患者，其CT和MRI表现极为不典型，呈现出“结节内结节”的外观。两名患者的放射性核素成像均显示，与正常肝脏相比，腺瘤内Ga-67摄取减少，腺瘤内胶体（Tc-99m植酸盐）摄取阴性，以及Tc-99m PMT早期摄取并随后滞留。这准确地描述了切除肿瘤独特的组织病理学特征。尽管CT和MRI表现各异，但联合使用放射性示踪剂的放射性核素成像可能在辅助诊断这种罕见的良性肿瘤方面发挥重要作用。
