Shershow J C, Kanarek D J, Kazemi H
Psychosom Med. 1976 Jul-Aug;38(4):282-7. doi: 10.1097/00006842-197607000-00007.
The ventilatory response to carbon dioxide (CO2 response) was determined in 18 patients admitted to an inpatient service with endogenous depressive illness. Admission mean CO2 response value for the group was below the mean value for a control group. At the time of hospital discharge marked clinical improvement had occurred in depressive symptomatology; mean CO2 response had increased slightly and was no longer significantly below the control value. CO2 response deserves further investigation as a possible physiologic characteristic of certain depressed patients.
对18名因内源性抑郁症入住住院部的患者测定了对二氧化碳的通气反应（CO2反应）。该组患者入院时的平均CO2反应值低于对照组的平均值。出院时，抑郁症状有了显著的临床改善；平均CO2反应略有增加，不再显著低于对照值。CO2反应作为某些抑郁症患者可能的生理特征值得进一步研究。
