Bekaroglu M, Soylu C, Soylu N, Bilici M
Department of Psychiatry, Faculty of Medicine, Karadeniz Technical University, Trabzon, Turkey.
Isr J Psychiatry Relat Sci. 1997;34(4):308-10.
Several cytogenetic surveys and literature reviews have suggested a possible association between Klinefelter's syndrome and bipolar illness. We describe a manic patient with Klinefelter's syndrome who was treated successfully with lithium. Our patient represents the 32nd reported case of bipolar disorder in an individual with a known chromosomal abnormality, the 15th with Klinefelter's syndrome, and the 11th with a karyotype of 47XXY.
多项细胞遗传学调查和文献综述表明，克兰费尔特综合征与双相情感障碍之间可能存在关联。我们描述了一名患有克兰费尔特综合征的躁狂患者，该患者用锂盐治疗成功。我们的患者是已知染色体异常个体中第32例报告的双相情感障碍病例，第15例患有克兰费尔特综合征，第11例核型为47XXY。
