Epidemiological characteristics of amniotic band sequence (ABS) and body wall complex (BWC): are they two different entities?

In 1965, Torpin [1965; Am J Obstet Gynecol 91:65-75] concluded that fetal constrictions and amputations were related to amniotic membrane rupture. Since then, this view was accepted widely, although different terms were used due to the variation in the types of associated anomalies. I consider that for those cases without body wall defects, the most appropriate term is amniotic band sequence (ABS), since amnion rupture could initiate a cascade of abnormalities (consequences) leading to the final structural defects. Here I present a clinical and epidemiological analysis of a series of consecutive infants with ABS, comparing their characteristics with those of infants with body wall complex (BWC). The results of this analysis suggest that ABS, from an epidemiological standpoint, is an entity different from BWC, and that amniotic bands in cases of BWC may be considered different from amniotic bands in cases without body wall defects. The former are probably produced earlier in the development than the latter.