Ballereau F, Merville C, Lafleuriel M T, Schrive I
Groupe d'Etudes Epidémiologiques et Prophylactiques (G.E.E.P), GIS Médicament, Université de Nantes, Faculté de pharmacie.
Bull Soc Pathol Exot. 1997;90(3):192-5.
A sodium hypochlorite solution (NaClO) containing 0.5% w/v of available chlorine (0.5% Cl2 or 5000 ppm) is a good and cheap solution for disinfecting material used to medical care. It is effective against bacteria, fungi and viruses. It is easy to prepare. It can be a good solution for antisepsis and disinfection in dispensaries in developing countries. However, it is not always easy to keep it in adequate conditions. That's the reason why we have evaluated the durability of such a solution of NaClO exposed to disadvantageous factors, specially daylight and air, and its antibacterial effectiveness. In this study, after exposure of NaClO containing 4350 ppm of available chlorine to these adverse conditions, the final concentration of NaClO was 2300 ppm of available chlorine and was found effective for decontamination of medical material. A protocol for conservation and use of a sodium hypochlorite solution (0.5% Cl2) in dispensaries of developing countries is proposed.
含有效氯0.5%(重量/体积)(0.5% Cl₂或5000 ppm)的次氯酸钠溶液(NaClO)是一种用于医疗护理用品消毒的优质且廉价的溶液。它对细菌、真菌和病毒均有效。它易于制备。对于发展中国家的药房而言,它可以是一种用于防腐和消毒的优质溶液。然而,要使其保持在适当条件下并非总是易事。这就是我们评估这种NaClO溶液在不利因素(特别是日光和空气)作用下的耐久性及其抗菌效果的原因。在本研究中,将含4350 ppm有效氯的NaClO暴露于这些不利条件后,最终NaClO的有效氯浓度为2300 ppm,且发现其对医疗用品的去污有效。本文提出了在发展中国家药房中保存和使用次氯酸钠溶液(0.5% Cl₂)的方案。