Jakubicz P, Leszczyńska K
Zakład Mikrobiologii Akademii Medycznej w Białymstoku.
Med Dosw Mikrobiol. 1997;49(1-2):55-60.
The study was undertaken to evaluate the incidence of Moraxella catarrhalis in patients with respiratory tract infections. Overall 514 specimens including 370 throat swabs and 114 sputum specimens were examined. The 78 strains isolated basing on morphological and biochemical characteristics were classified as Moraxella catarrhalis. The sensitivity of the strains to antibiotics was also estimated. The frequency of M. catarrhalis isolation from the throat swabs (15.9%) was higher than from the sputum (13.2%). Selected 25 specimens of sputum were tested simultaneously by quantitative and qualitative methods. Quantitative method was more sensitive (84% positive findings) than qualitative method (60% positive findings). Resistance to ampicillin was found in 52 (66.7%) strains of M. catarrhalis determined mainly by beta-lactamase production (over 70% strains were producers of beta-lactamase). All strains were sensitive to ofloxacin and amoxycillin/clavulanic acid combination. The frequency of M. catarrhalis isolation was higher in autumn-winter period than in summer (May-September). We conclude that M. catarrhalis, beside Streptococcus pyogenes (20.2%) and Streptococcus pneumoniae (17.1%), are the most frequently isolated bacteria in patients with respiratory tract infections.
本研究旨在评估呼吸道感染患者中卡他莫拉菌的发生率。共检查了514份标本，包括370份咽拭子和114份痰标本。根据形态学和生化特征分离出的78株菌株被分类为卡他莫拉菌。还评估了这些菌株对抗生素的敏感性。从咽拭子中分离出卡他莫拉菌的频率（15.9%）高于痰标本（13.2%）。选取25份痰标本同时采用定量和定性方法进行检测。定量方法（阳性检出率84%）比定性方法（阳性检出率60%）更敏感。在检测的卡他莫拉菌菌株中，52株（66.7%）对氨苄西林耐药，主要是由于产生β-内酰胺酶（超过70%的菌株是β-内酰胺酶产生菌）。所有菌株对氧氟沙星和阿莫西林/克拉维酸组合敏感。卡他莫拉菌的分离频率在秋冬季节高于夏季（5月至9月）。我们得出结论，卡他莫拉菌是呼吸道感染患者中除化脓性链球菌（20.2%）和肺炎链球菌（17.1%）外最常分离出的细菌。
