Delalande I, Thomas D, Forzy G, Hautecoeur P, Gallois P
Service de neurologie, hôpital Saint-Philibert, Lomme, France.
Neurophysiol Clin. 1997 Sep;27(4):293-9. doi: 10.1016/s0987-7053(97)85827-3.
This study was aimed at assessing the interest of middle latency auditory evoked potentials (MLAEP) recordings in multiple sclerosis (MS). Brainstem auditory evoked potentials (BAEP) and MLAEP were recorded in 40 control subjects and 65 patients who had MS according to Poser's criteria. Na and Pa latencies were significantly delayed in the MS group. These abnormalities were detected in 60% of the patients. In 26% of the cases with normal BAEP, abnormalities of MLAEP were present. In 71% of the patients abnormalities of both BAEP and MLAEP were observed. These results suggest the ability of MLAEP recordings to detect lesions of the auditory pathways rostral to the pons and show the value of their combined recordings in MS patients.
本研究旨在评估中潜伏期听觉诱发电位(MLAEP)记录在多发性硬化症(MS)中的应用价值。根据波泽标准,对40名对照受试者和65名MS患者进行了脑干听觉诱发电位(BAEP)和MLAEP记录。MS组的Na和Pa潜伏期显著延迟。60%的患者检测到这些异常。在BAEP正常的病例中,26%存在MLAEP异常。71%的患者同时观察到BAEP和MLAEP异常。这些结果表明MLAEP记录能够检测脑桥以上听觉通路的病变,并显示了其联合记录在MS患者中的价值。