Maccioni F, Broglia L, Rossi P
Istituto di Radiologia, Università degli Studi, La Sapienza, Policlinico Umberto I, La Sapienza, Roma.
Radiol Med. 1997 Jun;93(6):708-14.
We compared unenhanced and contrast-enhanced fast MRI and CT in the detection of liver metastases. Eleven patients with single or multiple hepatic lesions (42 in all) were submitted to CT and MR studies; T1- and T2-weighted TSE, T2-weighted TSE with fat suppression, unenhanced breath-hold TFE and early or delayed enhanced breath-hold TFE images were acquired with a 1.5 T super-conductive magnet (Philips NT). The quantitative analysis of all MR images was performed for contrast/noise ratio (CNR) and number of detected lesions; MR and CT images were also compared qualitatively for lesion conspicuity, anatomical structure identification and artifacts. The results were compared with Student's t test. Early enhanced breath-hold TFE was statistically superior to T1-weighted TSE (p = .0009), T2-weighted TSE (p = .01) and CT (p = .0004) for lesion conspicuity and to T1-weighted TSE, T2-weighted TSE, unenhanced TFE (p = .0001) and CT (p = .01) for anatomical structure identification. CT was superior to T1- and T2-weighted TSE (p = .0001) and unenhanced TFE (p = .004) for the lack of artifacts. Fat-suppressed T2-weighted TSE images had a statistically higher CNR than T2-weighted TSE (p = .02), T1-weighted TSE (p = .0006) and unenhanced and delayed TFE sequences (p = .007; p = .0001, respectively). To conclude, MRI appears superior to CT in the detection of liver metastases; the examination should include early enhanced breath-hold T1-weighted TFE and T2-weighted fat-suppressed TSE images.
我们比较了非增强和增强快速MRI及CT在检测肝转移瘤方面的效果。11例有单个或多个肝脏病变(共42个病变)的患者接受了CT和MR检查;使用1.5T超导磁体(飞利浦NT)采集了T1加权和T2加权快速自旋回波(TSE)、脂肪抑制的T2加权TSE、非增强屏气稳态自由进动(TFE)以及早期或延迟增强屏气TFE图像。对所有MR图像进行了对比度/噪声比(CNR)和检测到的病变数量的定量分析;还对MR和CT图像在病变清晰度、解剖结构识别和伪影方面进行了定性比较。结果采用学生t检验进行比较。对于病变清晰度,早期增强屏气TFE在统计学上优于T1加权TSE(p = 0.0009)、T2加权TSE(p = 0.01)和CT(p = 0.0004);对于解剖结构识别,优于T1加权TSE、T2加权TSE、非增强TFE(p = 0.0001)和CT(p = 0.01)。在无伪影方面,CT优于T1加权和T2加权TSE(p = 0.0001)以及非增强TFE(p = 0.004)。脂肪抑制的T2加权TSE图像的CNR在统计学上高于T2加权TSE(p = 0.02)、T1加权TSE(p = 0.0006)以及非增强和延迟TFE序列(分别为p = 0.007;p = 0.0001)。总之,在检测肝转移瘤方面,MRI似乎优于CT;检查应包括早期增强屏气T1加权TFE和T2加权脂肪抑制TSE图像。