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[计算机断层扫描与磁共振成像联合快速序列在有无顺磁性造影剂情况下对肝转移瘤评估的比较:定性与定量分析]

[Comparison of computerized tomography and magnetic resonance with fast sequences with and without paramagnetic contrast media in the assessment of liver metastasis: qualitative and quantitative analysis].

作者信息

Maccioni F, Broglia L, Rossi P

机构信息

Istituto di Radiologia, Università degli Studi, La Sapienza, Policlinico Umberto I, La Sapienza, Roma.

出版信息

Radiol Med. 1997 Jun;93(6):708-14.

PMID:9411518
Abstract

We compared unenhanced and contrast-enhanced fast MRI and CT in the detection of liver metastases. Eleven patients with single or multiple hepatic lesions (42 in all) were submitted to CT and MR studies; T1- and T2-weighted TSE, T2-weighted TSE with fat suppression, unenhanced breath-hold TFE and early or delayed enhanced breath-hold TFE images were acquired with a 1.5 T super-conductive magnet (Philips NT). The quantitative analysis of all MR images was performed for contrast/noise ratio (CNR) and number of detected lesions; MR and CT images were also compared qualitatively for lesion conspicuity, anatomical structure identification and artifacts. The results were compared with Student's t test. Early enhanced breath-hold TFE was statistically superior to T1-weighted TSE (p = .0009), T2-weighted TSE (p = .01) and CT (p = .0004) for lesion conspicuity and to T1-weighted TSE, T2-weighted TSE, unenhanced TFE (p = .0001) and CT (p = .01) for anatomical structure identification. CT was superior to T1- and T2-weighted TSE (p = .0001) and unenhanced TFE (p = .004) for the lack of artifacts. Fat-suppressed T2-weighted TSE images had a statistically higher CNR than T2-weighted TSE (p = .02), T1-weighted TSE (p = .0006) and unenhanced and delayed TFE sequences (p = .007; p = .0001, respectively). To conclude, MRI appears superior to CT in the detection of liver metastases; the examination should include early enhanced breath-hold T1-weighted TFE and T2-weighted fat-suppressed TSE images.

摘要

我们比较了非增强和增强快速MRI及CT在检测肝转移瘤方面的效果。11例有单个或多个肝脏病变(共42个病变)的患者接受了CT和MR检查;使用1.5T超导磁体(飞利浦NT)采集了T1加权和T2加权快速自旋回波(TSE)、脂肪抑制的T2加权TSE、非增强屏气稳态自由进动(TFE)以及早期或延迟增强屏气TFE图像。对所有MR图像进行了对比度/噪声比(CNR)和检测到的病变数量的定量分析;还对MR和CT图像在病变清晰度、解剖结构识别和伪影方面进行了定性比较。结果采用学生t检验进行比较。对于病变清晰度,早期增强屏气TFE在统计学上优于T1加权TSE(p = 0.0009)、T2加权TSE(p = 0.01)和CT(p = 0.0004);对于解剖结构识别,优于T1加权TSE、T2加权TSE、非增强TFE(p = 0.0001)和CT(p = 0.01)。在无伪影方面,CT优于T1加权和T2加权TSE(p = 0.0001)以及非增强TFE(p = 0.004)。脂肪抑制的T2加权TSE图像的CNR在统计学上高于T2加权TSE(p = 0.02)、T1加权TSE(p = 0.0006)以及非增强和延迟TFE序列(分别为p = 0.007;p = 0.0001)。总之,在检测肝转移瘤方面,MRI似乎优于CT;检查应包括早期增强屏气T1加权TFE和T2加权脂肪抑制TSE图像。

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