López Gil M, Arribas F, Velázquez M T, Casas P
Servicio de Cardiología, Hospital 12 de Octubre, Madrid.
Rev Esp Cardiol. 1997;50 Suppl 4:68-73.
The anatomical and tissue changes caused by hypertension are responsible of the higher incidence of atrial and ventricular arrhythmias as compared to normal population. Hypertension, when associated with atrial fibrillation, becomes an important risk factor for systemic embolism. Atrial dilatation and/or fibrosis because of haemodynamic overload due to left ventricular hypertrophy are the arrhythmic substrate. The higher incidence of ventricular arrhythmias is related to left ventricular hypertrophy. Ventricular premature beats, frequent and/or polymorphic in most of the cases, and short runs are the usual picture. Sustained ventricular tachycardia is seldom documented. The substrate is created by hypertrophy itself, resulting in conduction disturbances favoring reentry. Associated myocardial ischemia plays an important role in the genesis of ventricular arrhythmias. Left ventricular hypertrophy is associated with an increased incidence of total cardiac death and sudden death. Ventricular arrhythmias are suggested to be a poor prognostic factor. The aim of this article is to offer a simplified review of the meaning of cardiac arrhythmias in the hypertensive patient, and to give some clues to the practical approach in the clinical setting.
与正常人群相比,高血压引起的解剖学和组织学改变是心房和心室心律失常发生率较高的原因。高血压与心房颤动相关时,会成为系统性栓塞的重要危险因素。由于左心室肥厚导致血流动力学负荷过重引起的心房扩张和/或纤维化是心律失常的基础。室性心律失常的较高发生率与左心室肥厚有关。在大多数情况下,室性早搏频发和/或多形性,短阵发作较为常见。持续性室性心动过速很少有记录。其基础是肥厚本身导致的传导障碍,有利于折返。相关的心肌缺血在室性心律失常的发生中起重要作用。左心室肥厚与全因心脏死亡和猝死的发生率增加有关。室性心律失常被认为是一个不良的预后因素。本文旨在对高血压患者心律失常的意义进行简要综述,并为临床实践中的实际处理提供一些线索。