Sysoliatin P G, Vol'fovskiĭ V Z, Panin I A, Sysoliatin S P
Stomatologiia (Mosk). 1997;76(5):25-30.
The new method for surgical treatment of benign tumors and dysplastic processes in the facial skull bones includes resection of the involved segment of the bone, its mechanical treatment, extracorporeal freezing, sterilization, and replantation. Biophysical studies revealed that 10-min freezing of the preparation in liquid nitrogen followed by slow defrosting kills tumor cells. Animal experiments demonstrated excellent osteoplastic properties of thus treated replants. Based on the results of treatment of 29 patients, the authors defined the indications for such treatment and demonstrated its high efficacy in benign tumors and dysplastic processes in the facial skull.
面部颅骨良性肿瘤和发育异常性病变的外科治疗新方法包括切除受累骨段、进行机械处理、体外冷冻、消毒及再植。生物物理学研究表明，将标本在液氮中冷冻10分钟后缓慢解冻可杀死肿瘤细胞。动物实验证明，经如此处理后的再植骨具有良好的骨成形性能。基于对29例患者的治疗结果，作者明确了这种治疗方法的适应证，并证明其对面部颅骨良性肿瘤和发育异常性病变具有很高的疗效。
