Ismailov D B, Kanatbaeva A B, Aiubaev A S, Dosumova S M, Ushurova A I
Urol Nefrol (Mosk). 1997 Sep-Oct(5):43-5.
Clinical, urodynamic and neurological examinations of 30 children with hyperreflex dysfunction of the bladder gave evidence for clinical symptoms of natal trauma sequelae in 23 of them. Diagnosis of polyvisceral functional changes and chronic urinary diseases was made significantly more frequently in children with neurological symptoms. High occurrence of neurological symptoms of natal subclinical cervical traumas in children with hyperreflex dysfunction of the bladder suggests their pathogenetic relations. Hemodynamic changes of the cerebral vessels with affection of the venous outflow may cause hypoxia of the hypothalamo-hypophyseal structures with emergence of symptom complex of vegetovascular dystonia and marked neurogenic dysfunction of the bladder. The authors conclude on validity of pathogenetic neurological therapy to coordinate the activity of spinal and supraspinal centers regulating function of the bladder.
对30例膀胱反射亢进功能障碍患儿进行临床、尿动力学和神经学检查，结果显示其中23例有出生时创伤后遗症的临床症状。神经学症状患儿中，多脏器功能改变和慢性泌尿系统疾病的诊断更为常见。膀胱反射亢进功能障碍患儿中出生时亚临床颈部创伤的神经学症状发生率较高，提示它们之间的发病机制关系。脑血管血流动力学改变伴静脉流出受阻，可能导致下丘脑 - 垂体结构缺氧，继而出现植物神经血管性肌张力障碍症状复合体及明显的膀胱神经源性功能障碍。作者得出结论，发病机制性神经治疗对于协调调节膀胱功能的脊髓和脊髓上中枢的活动是有效的。
