Torres de Mercau G, Riviera de Martínez Villa N, Vitalone H, Mercau G, Gamundi S, Martínez Riera N, Soria N
Departmento Biomédico, Facultad de Medicina, Universidad de Tucumán.
Acta Gastroenterol Latinoam. 1997;27(2):63-5.
Sodium saccharin has found to be a tumoral promoter in the rat's bladder epithelium, property not demonstrated in humans. Nevertheless, at present there's no references on the possible alterations produced by sodium saccharin in the epithelium of the mice colon. In this work we describe the alterations produced by low doses of sodium saccharin in the epithelium of the mice colon. The changer produced by sodium saccharin consist in pleomorphic microvill with variations of form, length diameter and curvature and demonstrate by transmission electron microscopy.
已发现糖精钠是大鼠膀胱上皮中的肿瘤促进剂，这一特性在人类中未得到证实。然而，目前尚无关于糖精钠对小鼠结肠上皮可能产生的改变的参考文献。在这项工作中，我们描述了低剂量糖精钠对小鼠结肠上皮产生的改变。糖精钠产生的变化包括形态、长度、直径和曲率各异的多形性微绒毛，并通过透射电子显微镜得以证实。
