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[女性压力性尿失禁。尿道胶原注入治疗]

[Female stress urinary incontinence. Treatment with collagen infiltration in the urethra].

作者信息

Díaz Cabrera J A, Llerena Hoyos M, Ruiz Roldán M, Fuentes Lupiáñez C, Rodero García P, Aguayo Triano M, Burgos Rodríguez R

机构信息

Servicio de Urología, Hospital Regional de Málaga, España.

出版信息

Arch Esp Urol. 1997 Jul-Aug;50(6):655-9.

PMID:9412367
Abstract

OBJECTIVES

To present the results obtained in patients with stress urinary incontinence treated with periurethral collagen injection.

METHODS

26 female patients with stress urinary incontinence were treated with bovine collagen injection; mean volume 10.8 cc. The results achieved by this therapeutic modality are described herein.

RESULTS

Control evaluations performed during a period of one year showed highly satisfactory results had been achieved initially and the success rate gradually increased over the 12 months follow-up. Overall the final results showed a success rate of 34.6%, 38.4% showed frank improvement and 26.9% had a failed procedure. There were no significant differences in the results for both types of stress urinary incontinence. The results correlated with the severity of incontinence; the success rate was higher in the patients with low grade incontinence.

CONCLUSIONS

Periurethral collagen injection is indicated in patients with type I and type III stress urinary incontinence who cannot benefit from surgery. Patients with type II stress urinary incontinence, however, do not benefit from this therapeutic modality.

摘要

目的

介绍经尿道周围胶原注射治疗压力性尿失禁患者所取得的结果。

方法

26例压力性尿失禁女性患者接受了牛胶原蛋白注射治疗;平均注射量为10.8立方厘米。本文描述了这种治疗方式所取得的结果。

结果

在一年期间进行的对照评估显示,最初取得了非常令人满意的结果,并且在12个月的随访中成功率逐渐提高。总体而言,最终结果显示成功率为34.6%,38.4%有明显改善,26.9%治疗失败。两种类型的压力性尿失禁结果无显著差异。结果与尿失禁的严重程度相关;轻度尿失禁患者的成功率更高。

结论

经尿道周围胶原注射适用于无法从手术中获益的I型和III型压力性尿失禁患者。然而,II型压力性尿失禁患者无法从这种治疗方式中获益。

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Arch Esp Urol. 1997 Jul-Aug;50(6):655-9.
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