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甲状腺良性结节性疾病的甲状腺全切除术或叶切除术:手术方式的变化趋势

Total thyroidectomy or lobectomy in benign nodular disease of the thyroid: changing trends in surgery.

作者信息

Korun N, Aşci C, Yilmazlar T, Duman H, Zorluoglu A, Tuncel E, Ertürk E, Yerci O

机构信息

Department of Surgery, Uludağ University School of Medicine, Görükle, Bursa, Turkey.

出版信息

Int Surg. 1997 Oct-Dec;82(4):417-9.

PMID:9412844
Abstract

METHODS

Over a 23-month period (January 1994-December 1995) in the era of fine needle aspiration (FNA), 344 thyroid surgery operations were performed for benign diseases of the thyroid. Of these 55 total thyroidectomies or lobectomies were evaluated. Mean age was 43.6 + 9.7 and the female/male ratio was 47/8 (5.8). All cases were operated on with the consensus of the surgery + endocrinology + pathology council according to a protocol based on FNA, thyroid function tests, scintigraphy and ultrasound. Suspected FNA or suspected nodules during the surgery were verified by frozen section also. Of these 55 benign nodules, 7 (12.7%) had total bilateral, 48 (87.3%) unilateral lobectomies.

RESULTS

Postoperatively 3 cases (5.8%) of seroma, one transient hypoparathyroidism (1.8%) and one unilateral vocal cord paralysis (1.8%) were seen as complications.

CONCLUSIONS

In our center, FNA cytology has been a routine procedure since 1992. Surgery for benign thyroid disease has been reduced 50% since than. This study was started after two years of the FNA procedure. Resident nodules are the most common cause of recurrence in nodular thyroid disease, so some cases need radical surgery when it is decided to operate. Morbidity of surgery for recurrent disease is unacceptably high and is comparable to lifelong supplement therapy.

摘要

方法

在细针穿刺抽吸活检(FNA)时代,于1994年1月至1995年12月的23个月期间,对344例甲状腺良性疾病患者实施了甲状腺手术。对其中55例全甲状腺切除术或甲状腺叶切除术进行了评估。平均年龄为43.6±9.7岁,男女比例为47/8(5.8)。所有病例均经外科、内分泌科和病理科会诊后,根据基于FNA、甲状腺功能检查、闪烁扫描和超声检查的方案进行手术。手术中怀疑的FNA或结节也通过冰冻切片进行了验证。在这55个良性结节中,7例(12.7%)进行了双侧全切,48例(87.3%)进行了单侧甲状腺叶切除术。

结果

术后出现3例(5.8%)血清肿、1例短暂性甲状旁腺功能减退(1.8%)和1例单侧声带麻痹(1.8%)等并发症。

结论

在我们中心,自1992年以来FNA细胞学检查已成为常规操作。自那时起,甲状腺良性疾病的手术量减少了50%。本研究在FNA操作实施两年后开始。残留结节是结节性甲状腺疾病复发的最常见原因,因此在决定手术时,有些病例需要进行根治性手术。复发性疾病手术的发病率高得令人难以接受,且与终身补充治疗相当。

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