Basile-Borgia A, Abel J H
Department of Cardiovascular Perfusion, Easton Hospital, Easton, Pennsylvania 18042, USA.
Perfusion. 1997 Nov;12(6):349-56. doi: 10.1177/026765919701200603.
A broad range of molecular and cellular interactions contribute to various pathophysiological alterations in haemostasis. Recent studies have shown strong links between lipoproteins and coagulation factors. Findings suggest that lipoproteins play an important role in the fibrinolytic and thrombogenic mechanisms that influence the risks of patients in acute coronary syndromes. We will examine specific aspects of lipoproteins with reference to the effects of hyperlipidaemia on endothelial dysfunction and haemostasis, and its relevance in the patient presenting for revascularization.
广泛的分子和细胞相互作用导致了止血过程中的各种病理生理改变。最近的研究表明脂蛋白与凝血因子之间存在紧密联系。研究结果提示脂蛋白在影响急性冠状动脉综合征患者风险的纤溶和血栓形成机制中发挥重要作用。我们将参照高脂血症对内皮功能障碍和止血的影响，以及其在接受血运重建治疗的患者中的相关性，来探讨脂蛋白的具体方面。
