Bragin A G, Vinogradova O S, Emel'ianov V V
Zh Vyssh Nerv Deiat Im I P Pavlova. 1976 May-Jun;26(3):605-11.
In experiments with unanaesthetized rabbits the influences of electric stimulation of the dentate fascia (DF) on the extracellularly recorded spontaneous and evoked activity of the CA3 neurones were investigated. Stimulation of a fixed locus in the DF during recording in the CA3 by a microelectrode, shifted along the longitudinal axis of the hippocampus, supported the notion of the topical, "segmental" organization of connections between the DF and CA3. A relatively narrow "active zone" (approximately 700 nm) appeared in the CA3 during the threshold DF stimulation: it was bordered by zones with predominantly inhibitory responses to stimulation. The CA3 neurones in the "active zone" rapidly lost their reactivity to sensory stimuli. In the "inhibitory" and "zero" zones the normal level of reactivity to sensory stimuli was preserved.
在对未麻醉兔子进行的实验中，研究了电刺激齿状回（DF）对细胞外记录的CA3神经元自发和诱发活动的影响。在通过微电极在CA3进行记录时，刺激DF中一个固定位点，并沿海马体纵轴移动，这支持了DF和CA3之间连接存在局部“节段性”组织的观点。在阈值DF刺激期间，CA3中出现了一个相对狭窄的“活跃区”（约700纳米）：其边界区域对刺激主要产生抑制反应。“活跃区”中的CA3神经元对感觉刺激的反应性迅速丧失。在“抑制”区和“零”区，对感觉刺激的正常反应水平得以保留。
