慢性肝炎中的免疫复合物
Immune complexes in chronic hepatitis.
作者信息
Fodor O, Parau N, Fodor I, Radu D, Abrudan O
出版信息
Acta Hepatogastroenterol (Stuttg). 1976 Jun;23(3):172-6.
Rheumatoid factors were present in 33.2%, crioglobulins in 47.6%, and anticomplementary assay in 34.2% of cases with chronic active hepatitis. No statistically significant loss of total complement was observed, but its components especially C1 and C3, exhibited lowered titers in 48.6% and respectively 45.7% of 160 cases. The origin, significance and pathogenicity of these factors are discussed in connection with the presence and possible role of the immunologic complexes to the development of chronic liver injury.
在慢性活动性肝炎患者中，类风湿因子阳性率为33.2%，冷球蛋白阳性率为47.6%，抗补体试验阳性率为34.2%。未观察到总补体有统计学意义的降低，但其成分尤其是C1和C3，在160例患者中分别有48.6%和45.7%出现滴度降低。结合免疫复合物的存在及其在慢性肝损伤发展中的可能作用，对这些因子的来源、意义和致病性进行了讨论。
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