Müller-Schimpfle M, Stern W, Stoll P, Kaiser J W, Claussen C D
Abteilung Radiologische Diagnostik, Eberhard-Karls-Universität Tübingen.
Rofo. 1997 Oct;167(4):348-54. doi: 10.1055/s-2007-1015543.
To compare primary mammography diagnosis (ultrasound report available) with primary ultrasound diagnosis (mammography report available).
89 preoperative patients with suspicious lesions were included. Mammography and ultrasound of all patients were evaluated by two independent experienced readers under clinical conditions. The reports of the complementary modality were available to both observers. Lesion evaluation was done on a per breast basis, in cases of multiple lesions in respect of the lesion with the greatest risk of malignancy.
39 benign and 59 malignant lesions were found. Primary mammography and primary ultrasound yielded 3 and 8 false positives and 10 and 13 false negatives. Concerning the palpable lesions (n = 59), primary mammography and primary ultrasound had no and 4 false positives and 7 and 8 false negatives, respectively, for the non palpable lesions, the figures were 3 and 4 false positive and 3 and 5 false negatives.
Mammography remains the method of first choice in early detection of breast cancer, whereas breast ultrasound should be performed after and in knowledge of the mammogram, in consideration of the known indications (equivocal palpable lesion and mammographic opacity, dense breast).
比较乳腺钼靶初次诊断（可获取超声报告）与超声初次诊断（可获取乳腺钼靶报告）。
纳入89例术前有可疑病变的患者。两名经验丰富的独立阅片者在临床条件下对所有患者的乳腺钼靶和超声进行评估。两名观察者均可获取补充检查方式的报告。病变评估以每侧乳房为基础进行，对于存在多个病变的情况，则针对恶性风险最高的病变进行评估。
共发现39个良性病变和59个恶性病变。乳腺钼靶初次诊断和超声初次诊断分别产生3例和8例假阳性以及10例和13例假阴性。对于可触及病变（n = 59），乳腺钼靶初次诊断无假阳性，超声初次诊断有4例假阳性；对于不可触及病变，乳腺钼靶初次诊断有3例假阳性，超声初次诊断有4例假阳性，乳腺钼靶初次诊断有3例假阴性，超声初次诊断有5例假阴性。
乳腺钼靶仍然是早期乳腺癌检测的首选方法，而考虑到已知适应证（可触及病变不明确及乳腺钼靶影像不透明、乳腺致密），乳腺超声应在知晓乳腺钼靶检查结果之后进行。
