Winnefeld K
Institut für Klinische Chemie, Friedrich-Schiller-Universität, Jena.
Med Klin (Munich). 1997 Sep 15;92 Suppl 3:8-10. doi: 10.1007/BF03041949.
In all organisms with a metabolism of oxygen, radicals/reactive oxygen species appear. Normally a balance exists between formation and destruction of radicals. Many diseases show a disturbance of this balance with the destruction of biological structures. Results in patients with sepsis, terminal renal failure, bone marrow transplantation and cancer are given.
To avoid a possible pro-oxidative effect (vitamins C and E) and intoxications (selenium), before substitution a monitoring is necessary.
在所有具有氧代谢的生物体中,都会出现自由基/活性氧物种。通常,自由基的形成与破坏之间存在平衡。许多疾病都表现出这种平衡的紊乱,并伴有生物结构的破坏。文中给出了败血症、终末期肾衰竭、骨髓移植和癌症患者的相关结果。
为避免可能的促氧化作用(维生素C和E)和中毒(硒),在进行替代治疗之前需要进行监测。