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[前室间支肌桥致急性心肌梗死:支架植入术后血管穿孔的复杂病程]

[Acute myocardial infarct caused by a muscle bridge of the anterior interventricular ramus: complicated course with vascular perforation after stent implantation].

作者信息

Hering D, Horstkotte D, Schwimmbeck P, Piper C, Bilger J, Schultheiss H P

机构信息

Medizinische Klinik II, Kardiologie und Pulmologie, Universitätsklinik Benjamin Franklin, Freie Universität Berlin.

出版信息

Z Kardiol. 1997 Aug;86(8):630-8. doi: 10.1007/s003920050103.

Abstract

UNLABELLED

A 47-year-old male patient was admitted to our hospital with acute anterior myocardial infarction. Immediate coronary angiography was carried out, which showed proximal occlusion of the left anterior descending artery (LAD). After mechanical recanalization, a reduction in vessel caliber at the site of occlusion was visible, and balloon angioplasty with consecutive stent implantation because of vessel wall dissection was performed. After the procedure, diameter reduction of the entire vessel segment distal to the stent and muscular bridging with subtotal systolic obliteration of the LAD and one diagonal branch were demonstrated. Diastolic coronary flow did not appear to be limited (TIMI 3). Dipyridamole-thallium cardiac imaging revealed an incomplete perfusion defect of the anteroseptal region and a reversible perfusion reduction of the anterolateral region. For definitive treatment, we decided to implant a 3.0 mm-stent at the site of muscular bridging. Although balloon sizing was adapted to the diameter of the proximal reference segment, measured by quantitative coronary angiography, coronary perforation into the right ventricular outflow tract due to balloon oversizing in the distal dilation segment occurred. The patient remained asymptomatic at rest as well as under exercise testing, and hemodynamics remained stable. Coronary re-angiography after 1 week demonstrated a persistent fistula with complete opacification of the LAD and normal coronary flow (TIMI 3). Within the following 3 months, the coronary fistula closed spontaneously.

CONCLUSIONS

Muscular bridging is a rare cause of acute myocardial infarction. Balloon angioplasty and stent implantation in the bridged segment may be complicated by coronary artery perforation due to balloon oversizing. Risks and benefits of this therapeutic option, therefore, have to be critically evaluated, and careful selection of balloon size using measurements of proximal and distal reference diameter assessed by intravascular ultrasound is recommended. Coronary artery perforation into the myocardium with subsequent development of a fistula may be treated conservatively as long as the patient remains asymptomatic. The frequency of spontaneous closure of the fistula is high.

摘要

未标注

一名47岁男性患者因急性前壁心肌梗死入住我院。立即进行了冠状动脉造影,结果显示左前降支(LAD)近端闭塞。机械再通后,可见闭塞部位血管管径变窄,因血管壁夹层而进行了球囊血管成形术并连续植入支架。术后,显示支架远端整个血管段直径减小,LAD及其一个对角支存在肌桥伴收缩期几乎完全闭塞。舒张期冠状动脉血流似乎未受限制(TIMI 3级)。双嘧达莫-铊心肌显像显示前间隔区域存在不完全灌注缺损,前外侧区域灌注可逆性降低。为进行确定性治疗,我们决定在肌桥部位植入一枚3.0 mm支架。尽管球囊尺寸根据定量冠状动脉造影测量的近端参考节段直径进行了调整,但在远端扩张节段因球囊过大导致冠状动脉穿孔进入右心室流出道。患者在静息及运动试验时均无症状,血流动力学保持稳定。1周后冠状动脉造影显示持续存在瘘管,LAD完全显影且冠状动脉血流正常(TIMI 3级)。在接下来的3个月内,冠状动脉瘘自发闭合。

结论

肌桥是急性心肌梗死的罕见病因。在肌桥段进行球囊血管成形术和支架植入可能因球囊过大而并发冠状动脉穿孔。因此,必须严格评估这种治疗选择的风险和益处,并建议使用血管内超声测量近端和远端参考直径来仔细选择球囊尺寸。只要患者无症状,冠状动脉穿孔进入心肌并随后形成瘘管可保守治疗。瘘管自发闭合的频率很高。

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