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用于控制非洲血吸虫中间宿主的诱饵制剂的研发

Development of bait formulations for control of intermediate hosts of African schistosome species.

作者信息

Abdel-Hamid A Z

机构信息

Medical Chemistry Department, National Research Centre, Dokki, Cairo, Egypt.

出版信息

J Appl Toxicol. 1997 Nov-Dec;17(6):391-5. doi: 10.1002/(sici)1099-1263(199711/12)17:6<391::aid-jat456>3.0.co;2-i.

DOI:10.1002/(sici)1099-1263(199711/12)17:6<391::aid-jat456>3.0.co;2-i
PMID:9418947
Abstract

Exploration of methods of snail control indicated a need for a new method because many failures in control programmes are due to lack of contact between molluscicides and the target snail population. The incorporation of molluscicides inside food pellets that are attractive to and ingestible by the target snails is suggested. Different concentrations of alcoholic extracts of Ambrosia maritima, Cucumis prophetarum and Rhynchosia minima-molluscicides of plant origin-were compared with niclosamide (Bayluscide) which is a strong synthetic molluscicide. They were incorporated into attractive food pellets and the lethal doses were determined. The results showed that Biomphalaria alexandrina snails are sensitive to only bait formulations with low concentrations of molluscicides. Laboratory and semi-field trials were conducted to study the efficacy of the prepared bait formulations on Biomphalaria alexandrina snails. The stability of these bait formulations was studied and it was observed that their effectiveness was reduced after long storage periods (> 3 weeks). The results revealed that Ambrosia maritima was the most effective molluscicide.

摘要

蜗牛控制方法的探索表明需要一种新方法,因为许多控制计划的失败是由于杀软体动物剂与目标蜗牛种群之间缺乏接触。建议将杀软体动物剂掺入对目标蜗牛有吸引力且可食用的食物颗粒中。将不同浓度的滨海豚草、先知黄瓜和小巢菜(植物源杀软体动物剂)的酒精提取物与作为强力合成杀软体动物剂的氯硝柳胺(贝螺杀)进行了比较。将它们掺入有吸引力的食物颗粒中并测定致死剂量。结果表明,亚历山大双脐螺仅对低浓度杀软体动物剂的诱饵制剂敏感。进行了实验室和半田间试验,以研究制备的诱饵制剂对亚历山大双脐螺的功效。研究了这些诱饵制剂的稳定性,观察到长时间储存(>3周)后其有效性降低。结果显示,滨海豚草是最有效的杀软体动物剂。

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