Takeda T, Itai Y, Wu J, Ohtsuka S, Hyodo K, Ando M, Nishimura K, Hasegawa S, Akatsuka T, Akisada M
Institute of Clinical Medicine, University of Tsukuba, Ibaraki-ken, Japan.
Acad Radiol. 1995 Jul;2(7):602-8. doi: 10.1016/s1076-6332(05)80124-2.
For intravenous (i.v.) coronary arteriography, a real-time two-dimensional (2D) imaging system is being developed using above-K-edge monochromatic X-rays alone. The potential diagnostic value of this system was examined in the current study.
The angiographic system consisted of an asymmetric silicon (311) monocrystal, an image intensifier, and a charged-coupled device camera. It was constructed at the beam line of the Tristan Accumulation Ring. Monochromatic X-rays of 33.32 keV were used, and each image was recorded over 2 msec.
Ventricular wall motion and the anatomy of the coronary arteries could be seen in dogs by sequential images obtained without subtraction. The left anterior descending coronary artery, left circumflex coronary artery, and right coronary artery and the branches of these vessels were observed. The parts of the coronary arteries overlapping the aorta and left ventricle were revealed somewhat during washout of the contrast material.
For a 2D imaging system, monochromatic i.v. coronary angiography using an energy above the iodine K-edge might be able to image the coronary arteries without subtraction. However, the image quality needs to be improved by increasing the X-ray flux, decreasing background radiation scatter from the object, and decreasing contamination with 99-keV X-rays.
对于静脉冠状动脉造影，正在开发一种仅使用高于碘K边的单色X射线的实时二维（2D）成像系统。在本研究中检验了该系统的潜在诊断价值。
血管造影系统由一个不对称硅（311）单晶、一个影像增强器和一个电荷耦合器件相机组成。它是在特里斯坦积累环的束流线上构建的。使用33.32 keV的单色X射线，每个图像记录2毫秒。
通过未进行减影获得的连续图像，可以在狗身上看到心室壁运动和冠状动脉的解剖结构。观察到左冠状动脉前降支、左旋支、右冠状动脉及其分支。在造影剂冲洗过程中，部分与主动脉和左心室重叠的冠状动脉有所显示。
对于二维成像系统，使用高于碘K边能量的静脉单色冠状动脉造影可能无需减影就能对冠状动脉成像。然而，需要通过增加X射线通量、减少来自物体的背景辐射散射以及减少99 keV X射线的污染来提高图像质量。
