Good M I
Am J Psychiatry. 1976 Aug;133(8):948-52. doi: 10.1176/ajp.133.8.948.
The drug-automatism hypothesis implies a medication-induced absence of intentionality for self-poisoning and a relative amnesia for serial or single overdosage. Controversy stems from problems encountered in the formulation and verfication of the hypothesis. The author reviews the literature, presents a case associated with a proprietary sleeping preparation, and discusses psychopharmacological and psychophysiological elements in the mechanism of drug automatism and its differential diagnosis.
药物自动症假说意味着药物导致的自我中毒时缺乏故意性，以及对连续或单次过量用药存在相对遗忘。争议源于该假说在表述和验证过程中遇到的问题。作者回顾了相关文献，呈现了一个与一种专利睡眠制剂相关的病例，并讨论了药物自动症机制及其鉴别诊断中的精神药理学和心理生理学因素。
