Sagebiel R W
Melanoma Center, UCSF/Mt. Zion Medical Center, San Francisco 94120, USA.
Pathology (Phila). 1994;2(2):281-98.
The author outlines general principles and pitfalls in the pathologic interpretation of pigmented skin lesions, then focuses on issues related specifically to gross tissue specimens and to the histologic report. He concludes that definitive therapy for melanoma should not be based on partial biopsies, that frozen sections are not indicated, and that the pathologist should report all of the relevant histologic attributes whenever possible.
作者概述了色素沉着性皮肤病变病理诊断的一般原则和陷阱,然后重点讨论了与大体组织标本及组织学报告相关的问题。他总结认为,黑色素瘤的确定性治疗不应基于部分活检,不建议进行冰冻切片检查,并且病理学家应尽可能报告所有相关的组织学特征。