Barr R J
University of California, Irvine, USA.
Pathology (Phila). 1994;2(2):359-70.
The prognostic significance of clinical and histologic regression of malignant melanoma is highly controversial. Although small foci of regression in evolving malignant melanomas seem to have little or no effect on morbidity and mortality, extensive regression in larger, fully evolved lesions may be associated with poor prognosis. This chapter emphasizes the histologic features of regression and the patterns that are responsible for diagnostic pitfalls.
恶性黑色素瘤临床及组织学消退的预后意义极具争议性。虽然在进展期恶性黑色素瘤中出现的小灶性消退似乎对发病率和死亡率影响很小或没有影响，但在较大的、完全进展的病变中出现的广泛消退可能与预后不良有关。本章重点介绍消退的组织学特征以及导致诊断陷阱的模式。
