Some remarks to the histological classification of malignant melanoma of the skin and its prognostic values.

Histological classification of human skin malignant melanoma as recommended by WHO melanoma group renders the first useful orientation in regard to the biological behavior of the tumor, but it cannot give any further clinical outlook. It would be therefore desiderable to complete the histological examinations with enzymatic and immunologic examinations performed during the treatment of the patient and thus try to gain a basis for a prognostic evaluation.