输注Kell阳性血液后抗Kell抗体的发生率及持续时间。

Incidence and persistence of anti-Kell after transfusion of Kell-positive blood.

作者信息

Schabel A, König A L, Schiebel M R, Sugg U

机构信息

Institut für Transfusionsmedizin, Katharinenhospital, Stuttgart, Germany.

出版信息

Beitr Infusionsther Transfusionsmed. 1994;32:175-8.

PMID:9422111

Abstract

116 Kell-negative patients who had received at least one Kell-positive blood unit were tested about 3 and 12 months after transfusion. Antibody screening was performed by tube test and by gel centrifugation; both methods yielded identical results. After 3 months, anti-Kell was detected in 11 (9.5%) patients. Antibody titers using K+, k+ cells ranged from 1:1 to 1:128 with a predominance of low titers. Titers using K+, k- cells tended to be higher by one step; one anti-Kell could only be demonstrated with K+, k- cells. After about 12 months, anti-Kell could no longer be detected in 5 of the 11 patients (45.5%).

摘要

116名接受过至少一个Kell阳性血液单位输血的Kell阴性患者在输血后约3个月和12个月接受检测。通过试管试验和凝胶离心法进行抗体筛查；两种方法得出的结果相同。3个月后，在11名（9.5%）患者中检测到抗Kell抗体。使用K+、k+细胞检测的抗体效价范围为1:1至1:128，以低滴度为主。使用K+、k-细胞检测的效价往往高一个级别；一种抗Kell抗体仅用K+、k-细胞才能检测到。约12个月后，11名患者中有5名（45.5%）不再能检测到抗Kell抗体。