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由于自动抗体筛查无法检测到抗凯尔抗体导致的供者间不相容性。

Interdonor incompatibility due to anti-Kell antibody undetectable by automated antibody screening.

作者信息

West N C, Jenkins J A, Johnston B R, Modi N

出版信息

Vox Sang. 1986;50(3):174-6. doi: 10.1111/j.1423-0410.1986.tb04873.x.

Abstract

A unit of whole donor blood, the plasma of which contained anti-Kell antibody, was transfused into a Kell-negative patient who had received a unit of Kell-positive blood 4 weeks previously. A haemolytic transfusion reaction ensued. The antibody had gone undetected in routine automated screening of the donor blood. Automated antibody detection techniques do not offer reliable detection of anti-Kell antibodies.

摘要

一单位全血供体的血浆中含有抗凯尔抗体,该单位全血被输注给一名凯尔阴性患者,该患者在4周前接受过一单位凯尔阳性血液。随后发生了溶血性输血反应。在对供血者血液进行的常规自动筛查中,这种抗体未被检测到。自动抗体检测技术无法可靠地检测出抗凯尔抗体。

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