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儿童医疗程序中的氯胺酮麻醉。

Ketamine anaesthesia for medical procedures in children.

作者信息

Elliott E, Hanid T K, Arthur L J, Kay B

出版信息

Arch Dis Child. 1976 Jan;51(1):56-9. doi: 10.1136/adc.51.1.56.

DOI:10.1136/adc.51.1.56
PMID:942230
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1545857/
Abstract

Ketamine hydrochloride 2 mg/kg, together with atropine 0.2 mg, has been given intravenously on 100 occasions on a general paediatric ward. No serious side effects occurred. Dreams followed in 4 children but did not reduce acceptability of the drug. In our hands it has greatly reduced the pain and distress of children undergoing many routine medical procedures, particularly the dread which builds up when these have to be repeated in the same child. It has also produced close to ideal conditions for the operator, and probably increased his efficiency by reducing the emotional strain which occurs when doing painful things to a frightened patient.

摘要

在一家普通儿科病房,已对100例患儿静脉注射了2毫克/千克的盐酸氯胺酮以及0.2毫克阿托品。未发生严重副作用。4名儿童出现了梦境,但这并未降低该药物的可接受性。在我们手中,它极大地减轻了接受许多常规医疗程序的儿童的疼痛和痛苦,尤其是当这些程序必须在同一儿童身上重复进行时所产生的恐惧。它还为操作人员创造了近乎理想的条件,并且可能通过减轻对惊恐患者进行痛苦操作时产生的情绪压力而提高了操作人员的效率。

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Ketamine anaesthesia for medical procedures in children.儿童医疗程序中的氯胺酮麻醉。
Arch Dis Child. 1976 Jan;51(1):56-9. doi: 10.1136/adc.51.1.56.
2
Is atropine needed with ketamine sedation? A prospective, randomised, double blind study.氯胺酮镇静时需要使用阿托品吗?一项前瞻性、随机、双盲研究。
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[Ketamine-dehydrobenzperidol and ketamine-diazepam combinations for anaesthesia in neuro-radiology].
Anaesthesist. 1973 Mar;22(3):127-30.
4
Efficacy and safety of a mixture of ketamine, midazolam and atropine for procedural sedation in paediatric oncology: a randomised study of oral versus intramuscular route.氯胺酮、咪达唑仑和阿托品合剂用于儿科肿瘤程序性镇静的疗效与安全性:口服与肌内注射途径的随机研究
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Is prophylactic atropine necessary during ketamine sedation in children?儿童氯胺酮镇静期间预防性使用阿托品是否必要?
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Ketamine used for anaesthesia in children for pneumoencephalography.氯胺酮用于儿童气脑造影术的麻醉。
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The use of ketamine or ketamine-midazolam for adenotonsillectomy.氯胺酮或氯胺酮-咪达唑仑用于腺样体扁桃体切除术。
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Adjunctive atropine versus metoclopramide: can we reduce ketamine-associated vomiting in young children? a prospective, randomized, open, controlled study.附加阿托品与甲氧氯普胺:我们能否减少儿童使用氯胺酮后的呕吐?一项前瞻性、随机、开放、对照研究。
Acad Emerg Med. 2012 Oct;19(10):1128-33. doi: 10.1111/j.1553-2712.2012.01457.x. Epub 2012 Sep 25.
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本文引用的文献

1
PHARMACOLOGIC EFFECTS OF CI-581, A NEW DISSOCIATIVE ANESTHETIC, IN MAN.新型分离麻醉药CI - 581对人体的药理作用
Clin Pharmacol Ther. 1965 May-Jun;6:279-91. doi: 10.1002/cpt196563279.
2
Dissociative anesthesia with CI-581 in burned children.CI - 581用于烧伤儿童的分离麻醉。
Anesth Analg. 1967 Nov-Dec;46(6):719-24.
3
Ketamine: its place for neurosurgical diagnostic procedures.氯胺酮:其在神经外科诊断程序中的应用
Anesth Analg. 1969 Mar-Apr;48(2):181-8.
4
Electroencephalographic effects of ketamine anesthesia in children.氯胺酮麻醉对儿童脑电图的影响。
Anesth Analg. 1969 Jan-Feb;48(1):141-7.
5
Cardiovascular and respiratory function with CI-581.
Anesth Analg. 1968 Nov-Dec;47(6):760-8.
6
Alarming reactions to ketamine in patients taking thyroid medication--treatment with propranolol.服用甲状腺药物的患者对氯胺酮产生的不良反应——用普萘洛尔治疗
Anesthesiology. 1971 Aug;35(2):229-30. doi: 10.1097/00000542-197108000-00030.
7
Depression of laryngeal reflexes during keatmine anaesthesia.氯胺酮麻醉期间喉反射的抑制
Br Med J. 1971 Jun 19;2(5763):688-9. doi: 10.1136/bmj.2.5763.688.
8
Dissociative anesthesia: further pharmacologic studies and first clinical experience with the phencyclidine derivative CI-581.分离麻醉:苯环己哌啶衍生物CI-581的进一步药理学研究及首次临床经验
Anesth Analg. 1966 Jan-Feb;45(1):29-40.
9
British surgical aid to Jordan.英国对约旦的外科援助。
Ann R Coll Surg Engl. 1971 Nov;49(5):291-309.
10
Outpatient pediatric anesthesiology: a case series.门诊小儿麻醉学:病例系列
Anesth Analg. 1971 May-Jun;50(3):402-8.