Rogus R D, Smith M J, Kubo H D
Department of Radiation Oncology, University of California Davis Cancer Center, Sacramento 95817, USA.
Int J Radiat Oncol Biol Phys. 1998 Jan 1;40(1):245-8. doi: 10.1016/s0360-3016(97)00487-2.
To develop a simple equation that can be used to quickly QA check the total treatment time needed for straight or moderately bending, single-catheter implants from the treatment length and dose-prescription depth. A method to quickly check the total treatment time is useful for high dose rate (HDR) treatments, but may be most useful for intravascular patients that are catheterized while planning the treatment.
Nucletron-Oldelft treatment planning software was used to plan treatments with treatment lengths from 50 to 200 mm, and dose-prescription depths from 2 to 14 mm. For each plan, dose points were defined at a fixed depth away from the catheter. Doses were calculated, normalized, and optimized using the dose points. From these plans, a single equation was developed for the total treatment time as a function of treatment length and dose-prescription depth.
Total treatment time increases linearly with treatment length and supra-linearly with dose-prescription depth. A difference of 3% or more between the treatment time determined by the QA check equation and by the treatment planning software will alert the clinician and physicist to check for potential errors in dose prescription, prescription depth, source activity, treatment length, or inadvertent modifications to physics parameters used in the treatment planning software.
The simple equation that is developed can be used to quickly and accurately QA check the total treatment time needed for straight or moderately bending, single-catheter implants.
开发一个简单的公式,用于根据治疗长度和剂量处方深度快速对直线型或适度弯曲的单导管植入物所需的总治疗时间进行质量保证检查。一种快速检查总治疗时间的方法对高剂量率(HDR)治疗很有用,但对于在治疗计划时已插入导管的血管内患者可能最为有用。
使用Nucletron-Oldelft治疗计划软件规划治疗,治疗长度为50至200毫米,剂量处方深度为2至14毫米。对于每个计划,在距导管固定深度处定义剂量点。使用这些剂量点计算、归一、归一化并优化剂量。从这些计划中,开发了一个将总治疗时间作为治疗长度和剂量处方深度函数的单一公式。
总治疗时间随治疗长度呈线性增加,随剂量处方深度呈超线性增加。质量保证检查公式确定的治疗时间与治疗计划软件确定的治疗时间之间相差3%或更多,将提醒临床医生和物理师检查剂量处方、处方深度、源活度、治疗长度或对治疗计划软件中使用的物理参数的无意修改中是否存在潜在错误。
所开发的简单公式可用于快速准确地对直线型或适度弯曲的单导管植入物所需的总治疗时间进行质量保证检查。